Which medication must not be administered through the same IV line with blood products?

The medication that must not be administered through the same IV line with blood products is Calcium Gluconate. This is due to the risk of chemical reactions that may occur when calcium is introduced into the bloodstream alongside blood products. Calcium can cause clotting and may lead to the formation of precipitates, which can obstruct blood flow and compromise the effectiveness of the transfusion.

When administering blood products, it is standard practice to use a separate IV line, or at least a separate infusion set that can be easily flushed, to avoid any potential interactions that could adversely affect the patient's safety. Normal Saline is typically used to flush lines when infusing blood products and can safely run alongside the transfusion. Potassium Chloride can be dangerous when used improperly but doesn’t have the same direct issues with blood products as Calcium Gluconate. Heparin, while often contraindicated in certain situations involving blood products, does not present the same level of risk for clot formation and precipitate as calcium-based medications. Thus, Calcium Gluconate is the key medication to avoid in this context.